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Anavex Reports Fiscal Second Quarter 2015 Financial Results

(Forimmediaterelease.net) Anavex Life Sciences Corp. ("Anavex" or the “Company") (AVXL), a clinical-stage biopharmaceutical company developing drug candidates to treat Alzheimer's disease, other central nervous system (CNS) diseases, pain and various types of cancer, today reported financial results for the three and six months ended March 31, 2015.

Financial Highlights:

• Anavex had cash and cash equivalents of approximately $6.3 million as of March 31, 2015, compared with approximately $7.0 million as at December 31, 2014. Cash was used in operations and for the advancement of clinical trial work. The Company has sufficient cash for approximately two years and intends to use the majority to complete the ongoing Phase 2a clinical trial of ANAVEX 2-73 and ANAVEX PLUS.

• Operating expenses for the second quarter of fiscal year 2015 were approximately $0.8 million, compared to approximately $1.0 million for the quarter ended March 31, 2014. The decrease was primarily attributable to the one-time, non-cash charges during the comparative three-month period ended March 31, 2014. This was offset by an increase in research and development expenses in the current period, primarily related to the ongoing Phase 2a clinical trial of ANAVEX 2-73 and ANAVEX PLUS.

• The net loss for the second quarter of fiscal year 2015 was approximately $1.7 million or $0.03 per share, compared to net loss of approximately $1.0 million or $0.03 per share for the same period in 2014. The increased loss was primarily attributable to the non-cash charges during the current three-month period ended March 31, 2015.


“Our team has made exceptional progress to date in advancing both our clinical and business strategies," said Christopher U. Missling, PhD, President and Chief Executive Officer of Anavex. “The Phase 2a clinical trial of ANAVEX 2-73 and ANAVEX PLUS continues to progress, with preliminary data expected around the Q3 timeframe. We are excited by the potential of ANAVEX 2-73 as a potential platform drug for multiple neurodegenerative diseases beyond Alzheimer's and by our other advancing pipeline products in CNS as well as pain and cancer."

Recent Achievements

On April 23, 2015, Dr. Missling presented at the World Orphan Drug Congress in Washington, D.C. He discussed the role of sigma-1 receptors in additional indications beyond Alzheimer's disease. The Company stated that, in parallel with the ongoing Alzheimer's trial of ANAVEX 2-73 and ANAVEX PLUS, it is able to expand the development of ANAVEX 2-73 into rare or orphan CNS diseases.

On April 7, 2015, Anavex said it was encouraged by the findings of a new report in the latest issue of peer-reviewed scientific journal Neuroscience Letters. The study showed for the first time through real-time in vivo imaging how microglial inflammation, which is involved in devastating neurodegenerative diseases, can be resolved by sigma-1 receptor activation. The report underscored the potential therapeutic application of proprietary Anavex compounds in multiple neurological diseases.

On March 23, 2015, Anavex announced promising new preclinical data for both ANAVEX 2-73 and ANAVEX 3-71 (formerly AF710B), which was unveiled in two separate presentations at the 12th International Conference on Alzheimer's and Parkinson's Diseases and Related Neurological Disorders (AD/PD 2015) in Nice, France.

On March 17, 2015, Dr. Missling presented at 'The Physiopathology of Sigma-1 Receptors' symposium held at the Nice Sophia Antipolis University in Nice, France. His presentation, entitled 'Clinical trial design for Sigma-1 Receptor agonists,' included an overview of the Phase 2a clinical trial design of ANAVEX 2-73 and ANAVEX PLUS, which is ongoing in Alzheimer's patients.

On March 12, 2015, Anavex announced the appointment of Jacqueline French, MD, FAAN, to the Company's Scientific Advisory Board. An award-winning, internationally recognized expert on epilepsy, new therapeutic interventions and clinical trial methodology, Dr. French is Professor in the Department of Neurology at New York University (NYU), Co-Director of Epilepsy Research and Clinical Trials at NYU's Comprehensive Epilepsy Center and Director of the Epilepsy Study Consortium.

On March 5, 2015, Anavex announced the appointment of Corinne Lasmezas, DVM, PhD, to the Company's Scientific Advisory Board. A professor at The Scripps Research Institute for the past 10 years, Dr. Lasmezas is internationally recognized in the field of neurogenerative diseases with a focus now on studying the mechanisms of neurodegeneration.

On February 25, 2015, Anavex announced the findings of a research report in the current issue of peer-reviewed scientific journal Frontiers in Cellular Neuroscience. Among its conclusions, the report revealed that ANAVEX 2-73 prevents mitochondrial dysfunction and blocks resulting oxidative stress and apoptosis (cell death) in a nontransgenic mouse model of Alzheimer's disease. By preserving mitochondrial functionality and reducing other key AD hallmarks, Anavex said, its drug candidate ANAVEX 2-73 has the potential to prevent, stop, slow or reverse the disease, in addition to treating its symptoms.

The financial information for the three and six months ended March 31, 2015 should be read in conjunction with the Company's interim consolidated financial statements, which have been filed on U.S. Securities and Exchange Commission's EDGAR system and will be available on the Anavex website at www.anavex.com

About Anavex Life Sciences Corp.

Anavex Life Sciences Corp. (AVXL) is a publicly traded biopharmaceutical company dedicated to the development of novel drug candidates to treat central nervous system (CNS) diseases, pain and various types of cancer. The Company's lead drug candidates, ANAVEX 2-73 and ANAVEX PLUS, the combination of ANAVEX 2-73 and donepezil (Aricept(R)), are currently being evaluated in a Phase 2a clinical trial for Alzheimer's disease. ANAVEX 2-73 is an orally available drug candidate that targets sigma-1 and muscarinic receptors and has successfully completed a Phase 1 study with a clean data profile. Preclinical studies demonstrate its potential to halt and/or reverse the course of Alzheimer's disease. The drug combination, ANAVEX PLUS, produced up to 80% greater reversal of memory loss in Alzheimer's disease models versus when the drugs were used individually. Recent positive preclinical data indicates that ANAVEX 2-73 also exhibits anticonvulsant, anti-amnesic, neuroprotective and anti-depressant properties, indicating its potential to treat additional CNS disorders, including epilepsy and others.

Further information is available at www.anavex.com

Forward-Looking Statements

Statements in this press release that are not strictly historical in nature are forward-looking statements. These statements are only predictions based on current information and expectations and involve a number of risks and uncertainties. Actual events or results may differ materially from those projected in any of such statements due to various factors, including the risks set forth in the Company's most recent Annual Report on Form 10-K filed with the SEC. Readers are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date hereof. All forward-looking statements are qualified in their entirety by this cautionary statement and Anavex Life Sciences Corp. undertakes no obligation to revise or update this press release to reflect events or circumstances after the date hereof.


ANAVEX LIFE SCIENCES CORP.
CONSOLIDATED BALANCE SHEETS

ASSETS

March 31, September 30,
2015 2014
Current
Cash $ 6,310,643 $ 7,262,138
Prepaid expenses 51,985 89,117
Total current assets 6,362,628 7,351,255
Equipment 1,749 2,247
Total assets $ 6,364,377 $ 7,353,502

LIABILITIES AND STOCKHOLDERS' EQUITY

Current
Accounts payable and accrued liabilities $ 1,437,939 $ 1,249,084
Promissory notes payable 90,412 192,065
Total current liabilities 1,528,351 1,441,149
Non-interest bearing liabilities 133,727 5,719,727
Total liabilities 1,662,078 7,160,876
Common stock 64,876 47,201
Additional paid-in capital 59,082,325 52,078,750
Common stock to be issued 640,000 640,000
Accumulated deficit (55,084,902) (52,573,325)
Total stockholders' equity (capital deficit) 4,702,299 192,626
Total liabilities and stockholders' equity $ 6,364,377 $ 7,353,502

ANAVEX LIFE SCIENCES CORP.
INTERIM STATEMENTS OF OPERATIONS
THREE MONTHS ENDED MARCH 31, 2015

2015 2014

OPERATING EXPENSES
Research and development $ 407,146 $ 118,152
General and administrative 451,193 903,015
Total operating expenses 858,339 1,021,167

OPERATING LOSS (858,339) (1,021,167)

OTHER INCOME
Interest and finance expenses, net 2,228 (5,079)
Financing related charges and adjustments (912,357) (1,011)
Foreign exchange loss 43,609 8,397
Total other income (866,520) 2,307

NET LOSS $ (1,724,859) $ (1,018,860)

NET LOSS PER COMMON SHARE
BASIC $ (0.03) $ (0.03)
DILUTED $ (0.03) $ (0.03)

WEIGHTED AVERAGE NUMBER OF SHARES OUTSTANDING
BASIC 57,307,779 37,881,209
DILUTED 57,307,779 37,881,209

ANAVEX LIFE SCIENCES CORP.
INTERIM STATEMENTS OF OPERATIONS
SIX MONTHS ENDED MARCH 31, 2015

2015 2014

OPERATING EXPENSES
Research and development $ 725,771 $ 123,332
General and administrative 903,246 1,207,443
Total operating expenses 1,629,017 1,330,775

OPERATING LOSS (1,629,017) (1,330,775)

OTHER INCOME
Interest and finance expenses, net (74,781) (8,366)
Financing related charges and adjustments (874,706) 681,989
Foreign exchange loss 66,927 (3,071)
Total other income (882,560) 670,552

NET LOSS $ (2,511,577) $ (660,223)

NET LOSS PER COMMON SHARE
BASIC $ (0.05) $ (0.02)
DILUTED $ (0.05) $ (0.04)

WEIGHTED AVERAGE NUMBER OF SHARES OUTSTANDING
BASIC 54,437,890 37,680,823
DILUTED 54,437,890 37,680,823


For more information, contact:
Anavex Life Sciences Corp.
Research&Business Development
Toll-free: 1-844-689-3939
Email: href="mailto:info@anavex.com">info@anavex.com

Shareholder&Media Relations
Toll-free: 1-866-505-2895
Outside North America: +1 (416) 489-0092
Email: href="mailto:ir@anavex.com">ir@anavex.com
www.anavex.com

Company Name: Microcap Headlines, Inc. Contact Person: Nicole Peccia Email: info@microcapheadlines.com Phone: (877) 283-6422 Country: United States Website: www.microcapheadlines.com

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